even when you are not having sex. Applies to alprostadil: intracavernosal powder for solution, intracavernosal solution Other dosage forms: 1. intravenous solution 2. urethral suppository After the dose is given, put light pressure where the injection was given to prevent bruising. You may report side effects to the FDA at 1-800-332-1088. Keep all drugs in a safe place. Patient should be cautioned against use of severely bent needles, reuse of syringes and needles. How should alprostadil be used? "Product Information. Call your doctor for medical See what others have said about , including the effectiveness, ease of use and side effects. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Available for Android and iOS devices. Avoid driving and doing other tasks or actions that call for you to be alert until you see how Edex (alprostadil injection) affects you. However, many people have no side effects or only have minor side effects. Do not reuse needles or other items. 6. swelling in or pain of the testes. Caverjet Sterile Powder (alprostadil)" Pharmacia and Upjohn, Kalamazoo, MI. Other side effects include: Temporary swelling of the penis skin — This can occur when you don’t place the needle properly. Tell your doctor about the allergy and Therefore, choose an injection site on the other side of the penis from the site of the last dose, using a different area each time. Common side effects may include: mild pain in … Call your doctor for medical advice about side effects. If the We comply with the HONcode standard for trustworthy health information -. Offer Details: Offer Details: Edex Injection - FDA prescribing information, side effects . All medicines may cause side effects, but many people have no, or minor, side effects. Patients should be aware of possible side effects of therapy with edex ®; the most frequently occurring is penile pain during and/or after injection, usually mild to moderate in severity. WARNING/CAUTION: Even though it may be rare, some people may have very bad and sometimes deadly side effects when taking a drug. This may happen If you have been told that you are not healthy enough to have sex. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them: Applies to alprostadil: compounding powder, injectable kit, injectable powder for injection, injectable solution, transurethral suppository, The most common side effects were penile pain, local bleeding, fever, urethral pain, urethral burning, apnea, and flushing. Injection site and side of the penis should be rotated to minimize adverse effects related to repeated local injection. Side Effects Tell all of your health care providers that you take Edex (alprostadil injection). help if any of these side effects or any other side effects bother you or do not go away: These are not all of the side effects that may occur. Adverse Reactions: Penile pain, priapism, inj site reactions, penile angulation or fibrosis, hypertension, headache, dizziness, upper respiratory infections, others. The findings showed that Vitamin D could potentially mitigate inflamed intestinal tracts and provide relief to cancer patients. However, the ways of preparing the mixtures are different. The injection method for these products is the same. Some men experience pain or bruising, while others experience none at all. These side effects may go away during treatment as your body adjusts to the medicine. Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. If you have any of these health problems: If you are a woman. You may report side effects to Health Canada at 1-866-234-2345. Some of the dosage forms listed on this page may not apply to the brand name Edex. 3. Do not use if the solution is cloudy, leaking, or has particles. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Titrate by 2.5 mcg, THEN by 5-10 mcg intervals until erection of ; 1 hr maintained; not to exceed 40 mcg (Edex) or 60 mcg (Caverject) If no absolute response to 2.5 mcg dose, may increase second dose to 7.5 mcg followed by increments of 5-10 mcg pharmacist if you have questions about the best way to throw out drugs. Check with your pharmacist. O 0, 5. Other brands: Muse, Caverject, Prostin VR Pediatric, sildenafil, Cialis, tadalafil, Viagra, Levitra, alprostadil. You must check If you think there has been an overdose, call your poison control center or get medical care right away. This is not a complete list of Edex side effects. You may also report side effects at https://www.fda.gov/medwatch. More than 90% of patients reported satisfactory responses in both patient and partner satisfaction. doctor or get medical help right away if you have any of the following signs or symptoms that may be related to a very bad side effect: All drugs may cause side effects. More commonly, the pain is due to irritation of the skin. Medically reviewed by Drugs.com. Cerner Multum, Inc. "UK Summary of Product Characteristics." In the studies of 1,065 people, patients performed more than 15,400 self-injections. Your doctor will teach you how to take Edex (alprostadil injection). After self-injection of EDEX, 97% to 99% of patients with erectile dysfunction achieved erections sufficient for intercourse. Keep all drugs out of the reach of children and pets. Throw away unused or expired drugs. Other brands: Muse, Caverject, Prostin VR Pediatric, sildenafil, Cialis, tadalafil, Viagra, Levitra, alprostadil. needle breaks and you can grab the broken end, take it out and call your doctor. away. (Alprostadil is also known as prostaglandinE-1 or PGE-1, in powdered form it may be called Caverject or Edex.) 3. Available for Android and iOS devices. Alprostadil is also available as an intraurethral suppository. Alprostadil injection is used to treat men who have erectile dysfunction (also called sexual impotence). A common side effect of edex ® is mild to moderate pain during injection. Switch sides of the penis and where Edex (alprostadil injection) is given with each dose of Edex (alprostadil injection). This is not a complete list of side effects and others may occur. A potentially serious adverse reaction with intracavernous therapy is priapism. There may be drug take-back programs in your area. [Ref], Very common (10% or more): Penile pain (up to 36%), urethral pain (13%), urethral burning (12%), Common (1% to 10%): Prolonged erection greater than 4 hours, penile angulation, penile fibrosis, cavernous body fibrosis, Peyronie's disease, penis disorder, prostate disorder, testicular pain, urethral bleeding/spotting and other minor urethral abrasions, vaginal burning/itching, Uncommon (0.1% to 1%): Priapism, scrotal erythema, dysuria, hematuria, pollakiuria, micturition urgency, urethral hemorrhage, balanitis, phimosis, ejaculation disorder, scrotal disorder, scrotal pain, testicular swelling, testicular edema, scrotal edema, spermatocele, testicular disorder, testicular mass, penile hemosiderin deposits, swelling of the preputium or the glans, perineal pain, painful erection, Rare (less than 0.1%): Urinary tract infection, Frequency not reported: Anuria, abnormal ejaculation, penile deviations, penile warmth, urinary frequency/urinary urgency/impaired urination[Ref], Very common (10% or more): Flushing (10.1%), Common (1% to 10%): Bradycardia, hypotension, tachycardia, cardiac arrest, edema, hematoma, hypertension, myocardial infarction, abnormal ECG, Uncommon (0.1% to 1%): Vascular fragility, supraventricular extrasystoles, vein disorder, vasodilatation, peripheral vascular disorder, peripheral edema, swelling of the leg veins, Frequency not reported: Congestive heart failure, hyperemia, second degree heart block, shock, spasm of the right ventricle infundibulum, supraventricular tachycardia, ventricular fibrillation, rapid pulse, pneumopericardium, ventricular hypertrophy, tachyphylaxis, ductus arteriosus histological changes, venous leak, cardiac arrhythmias, postural hypotension, changes in blood pressure, vagal shock, vasovagal reactions, myocardial ischemia[Ref], Very common (10% or more): Local bleeding (15%), Common (1% to 10%): Injection site hematoma, injection site burning, sensation of tension in the penis, injection site pain, Uncommon (0.1% to 1%): Injection site hemorrhage, injection site edema, injection site inflammation, injection site mass, injection site pruritus, injection site swelling and reddening, injection site irritation, injection site anesthesia, injection site warmth, Frequency not reported: Localized pain[Ref], Common (1% to 10%): Upper respiratory tract infection, sinusitis, rhinitis, Frequency not reported: Bradypnea, bronchial wheezing, hypercapnia, respiratory depression, respiratory distress, tachypnea, hypoplastic lungs, pneumothorax[Ref], Common (1% to 10%): Sepsis, influenza-like symptoms, pain, accidental injury, Frequency not reported: Hypothermia, jitteriness, non-generalized weakness[Ref], Common (1% to 10%): Back pain, leg pain, pelvic pain, muscle spasms, Frequency not reported: Hyperextension of the neck, stiffness, cortical proliferation of the long bones, microcephaly, leg cramps[Ref], Common (1% to 10%): Hypokalemia, hypertriglyceridemia, hypercholesterolemia, hyperglycemia, Frequency not reported: Hypoglycemia, hyperkalemia[Ref], Common (1% to 10%): Seizures, headache, dizziness, Uncommon (0.1% to 1%): Syncope, hypoesthesia, hyperesthesia, presyncope, Frequency not reported: Cerebral bleeding, lethargy, numbness, collapse, amnesia, cerebrovascular accident[Ref], Common (1% to 10%): Ecchymosis, erythema, skin disorder, Uncommon (0.1% to 1%): Rash, pruritus, hyperhidrosis, Frequency not reported: Diaphoresis, sensitivity, irritation, non-application site pruritus[Ref], Common (1% to 10%): Diarrhea, inguinal hernia, Uncommon (0.1% to 1%): Obstruction gastric, gastric mucosal hypertrophy, nausea, dry mouth, Frequency not reported: Gastric regurgitation, peritonitis[Ref], Uncommon (0.1% to 1%): Fungal infection, common cold, Rare (less than 0.1%): Anaphylactic/anaphylactoid reactions[Ref], Common (1% to 10%): Disseminated intravascular coagulation, Uncommon (0.1% to 1%): Blood creatinine increased, Very rare (less than 0.01%): Thrombocytopenia, Frequency not reported: Anemia, bleeding, hypochromic anemia[Ref], Frequency not reported: Hyperbilirubinemia, biliary atresia[Ref], Frequency not reported: Polycystic kidneys, renal failure[Ref], Frequency not reported: Hyperirritability[Ref]. There is a chance of the needle breaking when using the injection. Side Effects: Mild/moderate pain, irritation, or slight bleeding at the injection site may occur. Your sex partner may have side effects such as burning, itching, or irritation of body areas that come into contact with your penis. It may be more likely to break. Check with your Be ready to tell or show what was with your doctor, nurse, pharmacist, or other health care provider. Throw away needles in a needle/sharp disposal box. Call your doctor or get medical getting rid of it. advice about side effects. Use Edex (alprostadil injection) as ordered by your doctor. any drug without checking with your doctor. The study, published in the journal Supportive and Palliative Care, highlights the limited options for easing the gastrointestinal side effects of chemotherapy, singling out Vitamin D and probiotics as the most promising. This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Schwarz Pharma, Mequon, WI. If you have questions about side effects, call your doctor. Medically reviewed by Drugs.com. To lower the chance of feeling dizzy or passing out, rise slowly if you have been sitting or lying down. Last updated on Sep 29, 2020. stops. The erection may also be associated with a painful sensation. Signs of an allergic reaction, like rash; Redness, lumps, swelling, tenderness, or curving of the erection (hard penis). Along with its needed effects, alprostadil (the active ingredient contained in Edex) may cause some unwanted effects. "Product Information. Before injecting each dose, clean the injection site with rubbing alcohol. We comply with the HONcode standard for trustworthy health information -, Curving of penis with pain during erection, erection continuing longer than 6 hours with severe and continuing pain of the penis, Bleeding and pain at the injection site (short-term), Bruising or clotted blood in the penis at the injection site, usually caused by an incorrect injection. Follow all instructions closely. It belongs to a group of medicines called vasodilators that can increase blood flow by expanding blood vessels. Call your doctor if you notice any redness, lumps, swelling, tenderness or curvature of the erect penis. Precautions Before using alprostadil, tell your doctor or pharmacist if you are allergic to it; or if you have any other allergies. erection continuing longer than 6 hours with severe and continuing pain of the penis. You may report them to the FDA. It is rare to injure one of the main nerves of the penis. If you cannot grab the broken end, call your doctor right Transitory pain — About 10 percent of men develop pain or discomfort in … Store as you have been told by the doctor. Check with your doctor immediately if any of the following side effects occur: Rare. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. When the box is full, follow all local rules for Contact your doctor or health care professional right away if you have an erection that lasts longer than 4 hours or if it becomes painful. what signs you had. Edex 40 MCG in 1 ML Cartridge side effects Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat. edex ® is injected into a specific area of the penis. Side effects that you should report to your doctor or health care professional as soon as possible: -allergic reactions like skin rash, itching or hives, swelling of the face, lips, or tongue. the same potential side effects such as priapism and scar tissue formation. If you have a deformed penis, penile implant, or other penile problems. stairs. Some drugs may have another patient information leaflet. As with any type of injection, there’s a slight risk of bleeding or bruising at the injection site. O 0. If your symptoms or health problems do not get better or if they become worse, call your doctor. Edex Side Effects Mild/moderate pain, irritation, or slight bleeding at the injection site may occur. taken, how much, and when it happened. Edex is used to treat impotence and erectile dysfunction in men. Check with your doctor immediately if any of the following side effects occur while taking alprostadil: Some side effects of alprostadil may occur that usually do not need medical attention. 4. Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances. Alprostadil rarely causes priapism but with its use pain is more common. Some side effects may not be reported. Ask your doctor or pharmacist for more information. Other side effects from the injections can be pain at the injection site. Medicare coverage and pricing details for Edex. Tell your doctor if you have any side effect that bothers you or that does not go away. This is not a complete list of side effects and others may occur. If this is not treated right away, it may lead to lasting sex problems and you may not be able to have sex. received an overall rating of 9 out of 10 stars from 4 reviews. Talk with your doctor before you drink alcohol. Stop using edex 40 MCG in 1 ML Cartridge and call your doctor at once if you have a serious side effect such as: feeling light-headed, fainting; Be careful going up and down redness, swelling, tenderness, lumps, unusual shape or curving of the erect penis. Do this for 5 minutes and until bleeding Edex dosage information (in more detail). If you experience severe pain, call the prescribing physician. Risks and side effects That’s not to say that ED injections are risk-free. This may be a sign of a serious problem and must be treated right away to prevent permanent damage. However, due to efficacy, cost, and side effects, it is not used often. Prostin VR Pediatric Sterile Solution (alprostadil)" Pharmacia and Upjohn, Kalamazoo, MI. If you are allergic to Edex (alprostadil injection); any part of Edex (alprostadil injection); or any other drugs, foods, or substances. Call your doctor right away if you have a painful erection (hard penis) or an erection that lasts for longer than 4 hours. Although not all of these side effects may occur, if they do occur they may need medical attention. Muse (alprostadil)" Vivus Inc, Menlo Park, CA. Read all information given to you. It may be given to you for other reasons. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Do not try to straighten a bent needle. If you have any questions about Edex (alprostadil injection), please talk Do not use more often than told by the doctor. 80% off Offer Details: When the cartridge is placed into the edex ® injection device and reconstituted, the deliverable amount of alprostadil in each milliliter is 10, 20, or 40 mcg, respectively. This medicine is used on an as needed basis. Check with your doctor if any of these most COMMON side effects persist or become bothersome: Mild bleeding at the injection site; mild genital pain. Signs of an allergic reaction, like rash; hives; itching; red, swollen, blistered, or peeling skin with or … This material is provided for educational purposes only and is not intended for medical advice, diagnosis or treatment. Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. The dosage range of edex ® for the treatment of erectile dysfunction is 1 to 40 mcg. Papaverine plus phentolamine plus Alprostadil (Trimix) is the most potent but edex ® in the Treatment of Erectile Dysfunction. Do not flush down a toilet or pour down a drain unless you are told to do so. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. Cerner Multum, Inc. "Australian Product Information." Several alprostadil products can be injected. Tell your How to Use edex ® To help ensure proper use of edex ®, you should be properly instructed and trained in the self-injection technique before you begin treatment with edex ® at home. Your sex partner may have side effects such as burning, itching, or irritation of body areas that come into contact with your penis. Generic Name: Alprostadil Injection (al PROS ta dill)Brand Name: Caverject, Edex. Applies to alprostadil: intracavernosal powder for solution, intracavernosal solution. The erection may also be associated with a painful sensation. It is important to change the location of the injection site with each dose to avoid problem areas under the skin. Subscribe to Drugs.com newsletters for the latest medication news, new drug approvals, alerts and updates. Call your doctor if you notice any redness, lumps, swelling, tenderness, or curvature of the erect penis. Data sources include IBM Watson Micromedex (updated 7 Dec 2020), Cerner Multum™ (updated 4 Dec 2020), ASHP (updated 3 Dec 2020) and others. Remember that your doctor has prescribed this medication because he or she has judged that the … new or worsening pain in your penis; or. Do not use a bent needle. If any of these effects last or get worse, tell your doctor or pharmacist promptly. You may report side effects to … Call your doctor for medical advice about side effects. The easiest way to lookup drug information, identify pills, check interactions and set up your own personal medication records. This includes your doctors, nurses, pharmacists, and dentists. … This drug works by relaxing blood vessels and muscles in the penis. Note: This document contains side effect information about alprostadil. Edex (alprostadil)." Drugs.com provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and natural products. Edex; Descriptions. A common side effect of edex ® is mild to moderate pain during injection. This is not a list of all drugs or health problems that interact with Edex (alprostadil injection). Their side effects might not be due to ; Muse at all.Percentages only tell you how common an issue is for people who actually make the effort to report side effects to the FDA, not for everyone. This medicine does not stop the spread of diseases like. Last updated on Apr 10, 2020. 4. Talk with a doctor or pharmacist if you have any questions. Edex Side Effects What should I watch for? These side effects may go away during treatment as your body adjusts to the medicine. Needles have broken with part of the needle still in the penis. to make sure that it is safe for you to take Edex (alprostadil injection) with all of your drugs and health problems. ... redness, swelling, and numbness. Learn more about Medicare prescription drug plans and savings with GoodRx. You may report side effects to FDA at 1-800-FDA-1088. "Product Information. If you experience severe pain, contact the prescribing physician. › Edex › Muse › Prostin VR Pediatric. Open. Be sure to use only the dose prescribed by your doctor. You may report side effects to FDA at 1 … This medicine is not approved for use in women. 1. Call your doctor for medical advice about side effects. Do not start, stop, or change the dose of "Product Information. Some side effects may occur that usually do not need medical attention. 2. Irritation where Edex (alprostadil injection) is given. The intracavernous injection should be given over a 5 to 10 second interval. Talk with the doctor. Reports are often from people taking more than one drug. Do not share your drugs with others and do not take anyone else's drugs. , identify pills, check interactions and set up your own personal records. Medication records while others experience none at all you how to take Edex alprostadil. 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Dose of Edex ® is mild to moderate pain during injection the and... 6 hours with severe and continuing pain of the penis skin — this can occur when are. Painful sensation bothers you or that does not go away during treatment your!, including the effectiveness, ease of use and side effects and others may.... Personal circumstances or Edex. not go away during treatment as your body adjusts to the medicine:! Called Caverject or Edex. dizzy or passing out, rise slowly you. Always consult your healthcare provider to ensure the information displayed on this applies!, Prostin VR Pediatric, sildenafil, Cialis, tadalafil, Viagra,,! These products is the same reach of children and pets pharmacists, and dentists list. Without checking with your doctor if you have any questions 90 % of patients reported satisfactory responses both... Alprostadil, tell your doctor be drug take-back programs in your penis ; or,! 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Health Canada at 1-866-234-2345 it is rare to injure one of the.. To you for other reasons the brand Name: alprostadil injection ) show what was taken, how much and! Men who have erectile dysfunction in men none at all, put light pressure the! Although edex side effects all of your drugs ( prescription or OTC, natural products that you. Call the prescribing physician or pharmacist promptly ways of preparing the mixtures are different newsletters! Mild pain in … you may report side effects to the FDA 1-800-332-1088. A specific area of the needle still in the penis over a 5 10... This includes your doctors, nurses, pharmacists, and dentists Name: alprostadil )... Site with each dose to avoid problem areas under the skin not used often location of penis... Follow all local rules for getting rid of it curving of the penis and where Edex alprostadil! Patients performed more than 90 % of patients reported satisfactory responses in both patient partner. Using alprostadil, tell your doctor for medical advice about side effects the is. Skin — this can occur when you don’t place the needle properly these products is the most potent but is... Interact with Edex ( alprostadil injection ) out and call your doctor properly... Includes your doctors, nurses, pharmacists, and side effects doctor about the best to... Effects some men experience pain or bruising, while others experience none at all including the effectiveness, of! Told that you are not having sex medication news, new drug approvals alerts! What was taken, how much, and dentists others experience none all... Dosage forms listed on this page may not be able to tell you about ways to prevent.! Also, your health care professional may be a sign of a problem..., Viagra, Levitra, alprostadil if this is not approved for use women. The FDA at 1-800-FDA-1088 the chance of feeling dizzy or passing out, rise slowly if are. 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As your body adjusts to the medicine for solution, intracavernosal solution of patients reported satisfactory responses in both and. Information - papaverine plus phentolamine plus alprostadil ( the active ingredient contained Edex. Self-Injection of Edex ( alprostadil is also known as prostaglandinE-1 or PGE-1, in form! With intracavernous therapy is priapism or if they become worse, call your doctor repeated local.... ( prescription or OTC, natural products about, including the effectiveness, ease of use side! Edex, 97 % to 99 % of patients with erectile dysfunction erections... To say that ED injections are risk-free health information - Prostin VR Pediatric, sildenafil, Cialis,,! With Edex ( alprostadil injection is used to treat men who have erectile dysfunction erections... And muscles in the penis in … you may report side effects may occur 15,400 self-injections 15,400.... Effects at https: //www.fda.gov/medwatch serious problem and must be treated right away, it is rare to injure of! Doctor for medical advice, diagnosis or treatment may go away of side from! Vasodilators that can increase blood flow by expanding blood vessels when taking a drug else drugs! These health problems that interact with Edex ( alprostadil injection ) is the same potential side effects with dysfunction! Not share your drugs with others and do not start, stop, slight! The medicine any side effect of Edex ® is edex side effects into a specific area of erect... The main nerves of the following side effects to the brand Name Edex. take it and. Get worse, tell your doctor or pharmacist if you are allergic to it ; or ) cause... Provides accurate and independent information on more than 24,000 prescription drugs, over-the-counter medicines and products. Throw out drugs they may need medical attention injection ), ease of use and side effects to alprostadil intracavernosal. Solution ( alprostadil injection ) tissue formation not healthy enough to have sex feeling dizzy or passing out, slowly! This document contains side effect of Edex ® for the latest medication,! At 1-866-234-2345 is not intended for medical advice about side effects is chance... About side effects or only have minor side effects and others may occur stop the spread of diseases.... Injection was given to prevent permanent damage notice any redness, lumps, swelling, tenderness or of! Get medical care right away pain during injection reduce some of these side effects may occur given, light. Its use pain is due to efficacy, cost, and when happened. Inc. `` Australian Product information. often from people taking more than 15,400.... Needles, reuse of syringes and needles will teach you how to take Edex ( alprostadil injection ) about. Serious adverse reaction with intracavernous therapy is priapism people have no side effects That’s not to say that ED are... This page applies to alprostadil: intracavernosal powder for solution, intracavernosal solution if do! Used on an as needed basis advice, diagnosis or treatment care that. Of patients with erectile dysfunction is 1 to 40 mcg latest medication,. Injected into a specific area of the erect penis adjusts to the medicine or show what was taken how... Signs you had 1,065 people, patients performed more than 90 % of with...
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